Prophylactic mastectomy may reduce your risk of breast cancer. Learn how doctors assess breast cancer risk and how prophylactic mastectomy may help prevent breast cancer. One such question is whether to have preventive mastectomy prophylactic mastectomy — surgery to remove one or both breasts in hopes of preventing or reducing your risk of breast cancer. Keep in mind that being identified as having high risk doesn't mean you're certain to get breast cancer. All it means is that your likelihood of developing the disease is several times higher than that of women with average risk.
Surgery to Reduce the Risk of Breast Cancer Fact Sheet - National Cancer Institute
Healthy women who carry a breast cancer-causing mutation in the BRCA1 gene, not only reduce their risk of developing the disease but also their chances of dying from it if they have both breasts removed, according to new research presented today Wednesday at the 11th European Breast Cancer Conference. However, the study also found that for women with a mutation in the BRCA2 gene, there was no difference in their chances of dying from the disease whether they opted to have their breasts removed bilateral risk-reducing mastectomy or BRRM or chose to have closer surveillance instead. The study of BRCA1 mutation carriers and BRCA2 mutation carriers in The Netherlands is the first to prospectively follow healthy women, who opted for either BRRM or surveillance, in order to compare their overall risk of dying from any cause and their risk of dying from breast cancer. The women were followed from the time of their DNA diagnosis the earliest was in January through to June , or the time of their death or last follow-up appointment. After an average follow-up time of approximately nine to 11 years, there were seven cases of breast cancer and 11 deaths one due to breast cancer among the BRCA1 mutations carriers who had BRRM, while there were breast cancer cases and 50 deaths 19 due to breast cancer in the surveillance group. At the same age, breast cancer-specific survival was For BRCA2 mutation carriers, after an average follow-up time of approximately nine to ten years, there were no cases of breast cancer and two deaths none due to breast cancer in the BRRM group, and breast cancer cases and 32 deaths seven due to breast cancer in the surveillance group.
Surgery to Reduce the Risk of Breast Cancer
Preventive mastectomy also called prophylactic mastectomy or risk-reducing mastectomy is the surgical removal of one or both breasts. It is done to prevent or reduce the risk of breast cancer in women and men who are at high risk of developing the disease. Research shows that preventive mastectomy may significantly reduce the chance of developing breast cancer in moderate- and high-risk women by about 90 percent.